Tag: vaccine

Prospects and Challenges of Genetically Modified Live-Attenuated Leishmania Vaccines

Prospects and Challenges of Genetically Modified Live-Attenuated Leishmania Vaccines

Announcing a new article publication for Zoonoses journal. Leishmaniases are transmitted by the protozoan parasite Leishmania through the bites of infected sandflies. Despite the availability of various medications, rising resistance and toxicity levels underscore the urgent need to explore and create a reliable, safe Leishmania vaccines for human use. Creating live attenuated promastigotes by genetically modifying […]

The Intra-Host Evolution of SARS-CoV-2 After Neutralizing Antibody Therapy, Revealed by Nanopore Sequencing

The Intra-Host Evolution of SARS-CoV-2 After Neutralizing Antibody Therapy, Revealed by Nanopore Sequencing

Announcing a new article publication for Zoonoses journal.   In the context of two Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) outbreaks involving local transmission and an international flight, the authors of this article used meta-transcriptome and multi-amplicon sequencing to successfully acquire the complete viral genome sequences from clinical samples with varying viral loads. To enhance […]

Nanoparticle-Based Vaccines against Zoonotic Viruses: A Review

Announcing a new article publication for Zoonoses journal. Vaccines are the most promising tools for maintaining public health. Most emerging human infectious diseases are caused by zoonotic viruses originating from an animal reservoir via zoonotic transmission. Therefore, zoonotic virus spillover and spread in humans have become global health threats. Nanoparticle-based vaccines are ideal for antigen […]

Zoonoses Best Published Papers Award 2022

  We are pleased to announce that two articles have been nominated for the Best Published Papers Award 2022 by the Editorial board of Zoonoses: SARS-CoV-2 Variants and Vaccination. Zoonoses. 2022. Vol. 2. DOI: 10.15212/ZOONOSES-2022-0001 Authors: Yang Liu, Jianying Liu, Pei-Yong Shi Keywords: SARS-CoV-2 variants, spike mutations, neutralization, vaccine, COVID-19 Publication Date: 08 February 2022 This paper […]

Yersinia pestis and Plague: Some Knowns and Unknowns

Announcing a new article publication for Zoonoses journal.   Since its first identification in 1894 during the third pandemic in Hong Kong, there has been significant progress in understanding the lifestyle of Yersinia pestis, the pathogen that is responsible for plague. Although we now have some understanding of the pathogen’s physiology, genetics, genomics, evolution, gene regulation, pathogenesis […]

SARS-CoV-2 Variants and Vaccination

Announcing a new article publication for Zoonoses journal. Over the past 2 years, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has continually evolved in human hosts, thus leading to the emergence of variants with altered viral transmission, disease severity, and evasion of immunity. Although vaccines for coronavirus disease 2019 (COVID-19) have been developed at an […]

Venezuelan Equine Encephalitis Virus V3526 Vaccine RNA-Dependent RNA Polymerase Mutants Increase Vaccine Safety Through Restricted Tissue Tropism in a Mouse Model

Announcing a new article publication for Zoonoses journal. Venezuelan equine encephalitis virus (VEEV) is an arbovirus endemic to the Americas, for which no vaccines or antiviral agents have been approved. TC-83 and V3526 are the best-characterized vaccine candidates for VEEV. Both are live-attenuated vaccines and have been associated with safety concerns, although fewer concerns exist […]

The Immungenicity and Cross-Neutralizing Activity of Enterovirus 71 Vaccine Candidate Strains

Announcing a new article publication for Zoonoses journal. In this commentary researchers from Beijing Minhai Biotechnology Co., Ltd., Beijing, China, Hubei Provincial Center for Disease Control and Prevention, Wuhan, China, Guangdong Provincial Institute of Biological Products and Drugs, Guangzhou, China, Gaozhou Center for Disease Control and Prevention, Guangdong, China and the Yangchun Center for Disease […]