Announcing a new article publication for Zoonoses journal. As infections caused by nontuberculous mycobacteria (NTM) are rapidly increasing globally, a need exists for developing novel antibiotics and discovering the mechanism of resistance. This research reported by this article was aimed at understanding the mechanism of bedaquiline resistance in the model NTM species Mycobacterium marinum (M. marinum). The Mycobacterium […]
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PRNP Sequences of Tibetan Antelope, Blue Sheep, and Plateau Pika from the Qinghai-Tibet Plateau and Reactivity of PrP Proteins to Rodent-Adapted Scrapie Strains in RT-QuIC and PMCA
Announcing a new article publication for Zoonoses journal. Tibetan antelope (Rhinopithecus), blue sheep (Pseudois nayauris), and plateau pika (Ochotona curzoniae) are wild animals living on the Qinghai-Tibet Plateau. There have been no reports of naturally-occurring transmissible spongioform encephalopathies (TSEs) involving these animals. Furthermore, the PRNP genes have not been described in the literature. The PRNP genes from 21 Tibetan […]
Yersinia pestis and Plague: Some Knowns and Unknowns
Announcing a new article publication for Zoonoses journal. Since its first identification in 1894 during the third pandemic in Hong Kong, there has been significant progress in understanding the lifestyle of Yersinia pestis, the pathogen that is responsible for plague. Although we now have some understanding of the pathogen’s physiology, genetics, genomics, evolution, gene regulation, pathogenesis […]
A Marked Decline in Taenia solium Taeniasis and Cysticercosis Infections in China: Possible Reasons from the Ecological Determinants Perspective
Announcing a new article publication for Zoonoses journal. Taenia solium taeniasis/cysticercosis is an important global food-borne infectious disease transmitted between humans and pigs. According to both national surveys and field investigations, the prevalence of the disease in China has significantly decreased in recent decades. The primary disease control measures are health education and promotion, meat inspection, […]
Novel Clinical and Genomic Signatures of the 2022 Monkeypox Virus
Announcing a new article publication for Zoonoses journal. The monkeypox outbreaks started in 2022 and became an unexpected public health emergency of international concern (PHEIC). The factors that drove this neglected zoonosis in Africa into a global focus are largely unknown. Combined clinical, epidemiologic, and phylogenomic analyses indicate that substantial genome mutations, deletions, and rearrangement […]
RNA-seq Analysis of the BCG Vaccine in a Humanized Mouse Model
Announcing a new article publication for Zoonoses journal. This study was aimed at screening differentially expressed genes (DEGs) and exploring the potential immune mechanism induced by the Bacillus Calmette-Guerin (BCG) vaccine in a humanized mouse model. Candidate DEGs between mice vaccinated with BCG or injected with PBS were identified through transcriptomics, and their biological […]
Development and Efficacy Evaluation of an SP01-adjuvanted Inactivated Escherichia Coli Mutant Vaccine Against Bovine Coliform Mastitis
Announcing a new article publication for Zoonoses journal. Escherichia coli (E. coli) is one of the most common pathogens causing clinical mastitis in cattle, but no vaccine is available to prevent this disease in China. Therefore, development of an E. coli vaccine against bovine clinical mastitis is urgently needed. In this research, the candidate vaccine (Ch-O111-1) and challenge […]
One Health Approach for the Control of Zoonotic Diseases
Announcing a new article publication for Zoonoses journal. Zoonoses are infectious diseases that can be transmitted from animals to humans and/or from humans to animals. Approximately 75% of new emerging and re-emerging disease pathogens are zoonotic: 60% spread from domestic and wild animals, and 80% are of concern regarding bioterrorism. For the past 20 years, […]
Microbial Communities in the Lungs of Bats in China
Announcing a new article publication for Zoonoses journal. Bats are the hosts of multiple pathogens, but the microbial composition of their lung tissues remains unknown. This study investigates the species compositions and genera of important respiratory tract pathogenic bacteria in bat lung tissue. A microbiota study was conducted in Hebei, Henan and Guizhou provinces in […]
In silico Design of a Crimean-Congo Hemorrhagic Fever Virus Glycoprotein Multi-Epitope Antigen for Vaccine Development
Announcing a new article publication for Zoonoses journal. No licensed vaccine is available to prevent the severe tick-borne disease Crimean-Congo hemorrhagic fever (CCHF), caused by the CCHF virus (CCHFV). This study sought to show that a combination of computational methods and data from published literature can inform the design of a multi-epitope antigen for CCHFV […]