Announcing a new article publication for Zoonoses journal. As global warming increases, mosquito activity areas are expanding, alongside changes in the natural environment and the misuse of insecticides, thus further increasing mosquito resistance and exposing the world to an elevated risk of mosquito-borne diseases. With advancements in gene editing technology, researchers are continually attempting to […]
Category: News and Events
Prospects and Challenges of Genetically Modified Live-Attenuated Leishmania Vaccines
Announcing a new article publication for Zoonoses journal. Leishmaniases are transmitted by the protozoan parasite Leishmania through the bites of infected sandflies. Despite the availability of various medications, rising resistance and toxicity levels underscore the urgent need to explore and create a reliable, safe Leishmania vaccines for human use. Creating live attenuated promastigotes by genetically modifying […]
Mycobacterium Tuberculosis Persister Cell Formation after Pyrazinamide Exposure
Announcing a new article publication for Zoonoses journal. Mycobacterium tuberculosis (Mtb) persister formation under antibiotic pressure is the main reason for long tuberculosis treatment and relapse. A key first-line antibiotic in TB treatment is pyrazinamide (PZA). The authors of this article established an in vitro assay, the time to detection (TTD) assay, to identify persister formation after PZA […]
Enhanced Expression of Two ISGs as Potential Biomarkers of Prognosis in HIV-Infected Immunological Non-Responders
Announcing a new article publication for Zoonoses journal. No novel biomarkers are currently available for evaluating immune reconstitution among people living with HIV/AIDS (PLWH) receiving combined antiretroviral treatment (cART). This study analyzed the expression patterns of interferon-stimulating genes (ISGs) in PLWH with the aim of identifying potential biomarkers for immune reconstitution. Study samples were collected […]
Oropouche Virus: More Questions than Answers
Announcing a new article publication for Zoonoses journal. Oropouche virus (genus Orthobunyavirus, family Peribunyaviridae) is an arthropod-borne virus that infects several species of animals and humans, primarily in South America. Despite being described as a human pathogen >60 years ago, little progress has been made towards describing the ecologic and pathologic characteristics of this pathogen. However, with […]
Detection and Genetic Analysis of Songling Virus in Haemaphysalis concinna near the China-North Korea Border
Announcing a new article publication for Zoonoses journal. Songling virus (SGLV) is a spherical, enveloped, fragmented, negative-stranded RNA virus belonging to the genus Orthonairovirus in the Nairoviridae family. SGLV is transmitted by ticks and can cause disease in humans. This study identified and characterized SGLV in Haemaphysalis concinna ticks collected in 2023 in the Yanbian Korean Autonomous Prefecture (China) near the […]
Spotted Fever Group rickettsiae are the Dominant Pathogens in Parasitic Rhipicephalus microplus in Yunpan and Menghun, Xishuangbanna, Yunnan Province, China
Announcing a new article publication for Zoonoses journal. Distribution of the bacterium flora in ticks has an essential role in mapping and preventing local tick-borne diseases. The purpose of this study was to map the bacterium flora and identify the main pathogens in ticks in grazing areas of Yunnan province. The V3-V4 region of 16S […]
Unveiling Disease X: Strategies for Tackling the New Frontier of Infectious Diseases
Announcing a new article publication for Zoonoses journal. Disease X stands as a symbol for a subset of emerging infectious diseases rising to prominence as a significant challenge to global health security. This comprehensive review delves into the historical context, precise definition, and illustrative case studies of disease X, including notable examples, such as COVID-19, […]
Long-Term Protection from SARS-CoV-2 Variants in Mice by a Phase II Clinically Evaluated Original mRNA Vaccine Booster
Announcing a new article publication for Zoonoses journal. The global coronavirus disease 2019 (COVID-19) pandemic was caused by SARS-CoV-2. This article discussed the development of an mRNA vaccine (LVRNA009) that encoded the S protein of the Wuhan-Hu-1 strain and evaluated the long-term protection potential against SARS-CoV-2 variants. Mice were initially vaccinated with 2 doses of […]
Global Distribution and Prediction of Transmission-Risk of Visceral Leishmaniasis
Announcing a new article publication for Zoonoses journal. Visceral leishmaniasis (VL) is a vector-borne disease posing increasing public health concerns. Although efforts to eliminate VL are underway, its global risk distribution remains unclear, because of changes in transmission risk. Worldwide province-level data on VL incidence were obtained from multiple sources. The authors of this article […]