To improve the understanding of zoonoses and facilitate the management of the diseases, a thematic series entitled “Management of Viral Hepatitis in the Post-Omics Era” is now open for article submission. Zoonoses seeks original research, review, mini review, hypothesis and theory, submissions pertaining to the latest knowledge on diagnosis of viral hepatitis; screening of prognostic markers and model construction with multi-omics technology; multi-omics of viral hepatitis, including proteomics, metabonomics, transcriptomics; epidemiology, prevention and treatment system and vaccine development of hepatitis; evaluation of therapeutic effect of anti-hepatitis virus therapy, etc.; host immunity of hepatitis virus and the global burden of hepatitis.
Five different types of hepatitis viruses (HAV, HBV, HCV, HDV, and HEV) are recognized as etiologic agents for hepatitis A, B, C, D and E, respectively. Most of them are RNA viruses, expect for HBV (a DNA virus). These hepatitis viruses are different in the transmission routes and high-risk populations. Effective response needs the joint development of clinical and basic research, and at the same time, it needs to carry out tailored intervention for each virus.
Early diagnosis of hepatitis infection and early evaluation of its prognosis are very important for effective treatment and nursing. Due to the lack of awareness of viral hepatitis, people often ignore antiviral treatment, leading to disease progression. Efficient and accurate diagnosis of viral hepatitis is of importance for treatment and evaluation of disease prognosis.
Through this special issue, we wish to promote the development of new methods for diagnosis and prognosis evaluation of patients with viral hepatitis, explore/validate new markers for antiviral efficacy evaluation with multi-omics technology and share new ideas for the diagnosis and treatment of viral hepatitis.
State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China
Infectious Disease; Hepatitis E virus, Diagnosis, Extrahepatic manifestations, Mechanism of severity; Microecology; Proteome
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, Zhejiang University, Hangzhou, China
Proteomics, Metabolomics, Mass spectrometry, Viral Hepatitis; Liver failure; viral host interaction
Department of Infectious Diseases, the First Affiliated Hospital of Nanchang University, Jiangxi Province, China
Basic and clinical research on viral hepatitis; Liver fibrosis and liver failure.
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