Tag: pattern recognition receptors

Protective Immunity and Immunopathology in Ehrlichiosis

Announcing a new article publication for Zoonoses journal.  Human monocytic ehrlichiosis, a tick transmitted infection, ranges in severity from apparently subclinical to fatal toxic shock-like disease. Models in immunocompetent mice range from abortive to uniformly lethal infection, depending on the Ehrlichia species, inoculum dose, and inoculation route. Effective immunity is mediated by CD4+ T lymphocytes and gamma interferon. […]