Tag: Orientia tsutsugamushi

Scrub Typhus Diagnostics: The Present and the Future

Scrub Typhus Diagnostics

Announcing a new article publication for Zoonoses journal. Scrub typhus, caused by Orientia tsutsugamushi, is a vector-borne, zoonotic disease commonly occurring in a geographic region known as the ‘tsutsugamushi triangle’. Scrub typhus causes acute undifferentiated febrile illness (AUFI) with non-specific clinical features and is difficult to diagnose when a highly characteristic but not pathognomonic eschar is […]

Molecular Diagnosis of Scrub Typhus: Sample and Timing Matter

Announcing a new article publication for Zoonoses journal.  Scrub typhus (ST) is an acute febrile illness caused by Orientia tsutsugamushi. Laboratory tests are needed to confirm the diagnosis when the characteristic eschar is absent. This study aimed to evaluate the performance of 47 kDa qPCR using clotted and EDTA-treated blood among patients with suspected ST Clotted […]

Pattern Recognition Receptors in Innate Immunity to Obligate Intracellular Bacteria

Announcing a new article publication for Zoonoses journal. Researchers from University of Texas Medical Branch, Galveston, TX, USA review pattern recognition receptors in innate immunity to obligate intracellular bacteria. Host pattern recognition receptors (PRRs) are crucial for sensing pathogenic microorganisms, initiating innate responses, and modulating pathogen specific adaptive immunity during infection. Rickettsia spp., Orientia tsutsugamushi, […]