Tag: Mycobacterium tuberculosis

RNA-seq Analysis of the BCG Vaccine in a Humanized Mouse Model

Announcing a new article publication for Zoonoses journal.  This study was aimed at screening differentially expressed genes (DEGs) and exploring the potential immune mechanism induced by the Bacillus Calmette-Guerin (BCG) vaccine in a humanized mouse model.   Candidate DEGs between mice vaccinated with BCG or injected with PBS were identified through transcriptomics, and their biological […]

Identification of N-formylated Peptides with Neutrophilic Chemotactic Activity in Mycobacterium tuberculosis

Announcing a new article publication for Zoonoses journal. Neutrophil infiltration of the lungs is associated with granuloma formation and the severity of tuberculosis infection. Although several cytokines and chemokines are known to contribute to lung neutrophil infiltration, the neutrophilic chemotactic factors of Mycobacterium tuberculosis (Mtb) remain unexplored. The authors of this paper performed Transwell based chemotactic assays […]