The First Molecular Characterization of Pediatric Visceral Leishmaniasis in Jordan

Announcing a new article publication for Zoonoses journal.  Leishmaniasis is a neglected endemic, vector-borne tropical disease that poses a substantial public health threat in Jordan, yet data on visceral leishmaniasis, particularly in human cases, remain limited.  Three pediatric cases presenting symptoms of visceral leishmaniasis in Jordan are clinically evaluated. Diagnosis was confirmed according to bone marrow aspirates, cytology, molecular techniques, and sequencing to identify the causative Leishmania species.

Two cases were caused by L. infantum, and one case was caused by L. tropica. The sequences of the studied samples showed a high similarity to regional isolates instead of the isolated strains showed close genetic similarity to regional isolates. The identification of autochthonous human visceral leishmaniasis cases in Jordan is a critical public health concern. The emergence of such cases in new geographic areas might strain healthcare services, particularly for vulnerable populations. Improved surveillance, research, and crisis management plans for both human and canine leishmaniasis in Jordan are urgently needed.

Read More: https://www.scienceopen.com/hosted-document?doi=10.15212/ZOONOSES-2025-0035

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 eISSN 2737-7474

ISSN 2737-7466

Wael Hananeh, Renad Alzou’bi and Raida Al Rukibat et al. The First Molecular Characterization of Pediatric Visceral Leishmaniasis in Jordan. Zoonoses. 2025. Vol. 5(1). DOI: 10.15212/ZOONOSES-2025-0035