Tag: scrub typhus

Humoral Immune Response to Orientia tsutsugamushi Infection: Recent Research Findings and Future Studies

Orientia tsutsugamushi

Announcing a new article publication for Zoonoses journal. Orientia tsutsugamushi (Ot), an intracellular bacterium in the family Rickettsiaceae, is the etiological agent of scrub typhus. Understanding of the immunologic responses to Ot infection, particularly immunity after infection, has remained a major knowledge gap. Although anti-Ot IgG appears to be short-lived in infected humans, recent studies have reported autoreactive IgM […]

Evaluation of Real Time PCR Detection of the 47 kDa Gene for Reliable Diagnosis of Pediatric Scrub Typhus

Reliable Diagnosis of Pediatric Scrub Typhus

Announcing a new article publication for Zoonoses journal. Diagnosis of scrub typhus is difficult, because of its non-specific clinical features and a lack of reliable serological assays. This study assessed real time PCR detection of the 47 kDa gene along with routine IgM ELISA for confirmatory diagnosis of scrub typhus. This observational study was conducted […]