Announcing a new article publication for Zoonoses journal. This study analyzed the distribution and progression of prion seeds across the central nervous system (CNS) and peripheral tissues, by evaluating the real time quaking-induced conversion (RT-QuIC) reactivity of the brain, and other organs and tissues, from hamsters in early, middle-early, middle-late and terminal stages of intracerebral […]
Tag: RT-QuIC
PRNP Sequences of Tibetan Antelope, Blue Sheep, and Plateau Pika from the Qinghai-Tibet Plateau and Reactivity of PrP Proteins to Rodent-Adapted Scrapie Strains in RT-QuIC and PMCA
Announcing a new article publication for Zoonoses journal. Tibetan antelope (Rhinopithecus), blue sheep (Pseudois nayauris), and plateau pika (Ochotona curzoniae) are wild animals living on the Qinghai-Tibet Plateau. There have been no reports of naturally-occurring transmissible spongioform encephalopathies (TSEs) involving these animals. Furthermore, the PRNP genes have not been described in the literature. The PRNP genes from 21 Tibetan […]