Tag: LymeDisease

Development of a Colloidal Gold Immunochromatographic Strip for Rapid Serological Detection of Antibodies to Borrelia burgdorferi in Canines

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Announcing a new article publication for Zoonoses journal.  This study was aimed at developing and preliminarily validating a colloidal gold immunochromatographic lateral flow (ICLF) strip for rapid serological screening of antibodies to Borrelia burgdorferi in canine serum. An OspC-BmpA fusion antigen was expressed in Escherichia coli, purified, and used to assemble an antigen-based ICLF strip. Analytical performance was […]

How Prevalence Influences the Interpretation of Lyme Disease Test Results in a High-Incidence State (Wisconsin) Versus a Low-Incidence State (Arkansas)

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Lyme disease

Announcing a new article publication for Zoonoses journal. Clinicians’ understanding of prevalence is key in diagnostic test interpretation. In high-prevalence scenarios, the post-test probability of a positive test result can approach 100%, whereas in low-prevalence situations, the post-test probability might only slightly exceed the initial low pre-test probability. In this article an example of this […]