{"id":690,"date":"2022-06-14T14:16:09","date_gmt":"2022-06-14T14:16:09","guid":{"rendered":"https:\/\/zoonoses-journal.org\/?p=690"},"modified":"2022-06-14T14:16:09","modified_gmt":"2022-06-14T14:16:09","slug":"research-advances-in-bourbon-virus-a-tick-borne-thogotovirus-of-the-orthomyxovirus-family","status":"publish","type":"post","link":"https:\/\/zoonoses-journal.org\/index.php\/2022\/06\/14\/research-advances-in-bourbon-virus-a-tick-borne-thogotovirus-of-the-orthomyxovirus-family\/","title":{"rendered":"Research Advances in Bourbon Virus, a Tick-borne Thogotovirus of the Orthomyxovirus Family"},"content":{"rendered":"<p>Announcing a new article publication for <em>Zoonoses<\/em> journal. Bourbon virus (BRBV) was first isolated from a blood sample collected from a male patient living in Bourbon County, Kansas, during the spring of 2014. The patient later died because of complications associated with multiorgan failure. Several deaths due to BRBV infection have since been reported in the United States, and misdiagnosed cases are often undercounted. BRBV is a member of the genus\u00a0<em>Thogotovirus<\/em>\u00a0of the\u00a0<em>Orthomyxoviridae<\/em>\u00a0family, and is transmitted through the Lone Star tick,\u00a0<em>Amblyomma americanum<\/em>, in North America. Currently, no specific antiviral agents or vaccines are available to treat or prevent BRBV infection. Several small-molecular compounds have been identified to effectively inhibit BRBV infection of\u00a0<em>in vitro<\/em>\u00a0cell cultures at the single- or sub-micromolar level. Favipiravir, an RNA-dependent RNA polymerase inhibitor, has been found to prevent death in type I interferon receptor knockout mice with BRBV infection.<\/p>\n<p><strong>Article reference:<\/strong> Siyuan Hao, Kang Ning and \u00c7a\u011fla Aksu K\u00fcz et al. Eight Years of Research Advances in Bourbon Virus, a Tick-borne Thogotovirus of the Orthomyxovirus Family.\u00a0<em>Zoonoses.\u00a0<\/em>Vol. 2(1). DOI: 10.15212\/ZOONOSES-2022-0012<\/p>\n<p><strong>Keywords:<\/strong> Bourbon virus, Lone Star tick, infection, antiviral agents<\/p>\n<p><em>Zoonoses<\/em> is fully open access journal for research scientists, physicians, veterinarians, and public health professionals working on diverse disciplinaries of zoonotic diseases.<\/p>\n<p><em>Zoonoses<\/em> is now open for submissions; articles can be submitted online at <a href=\"https:\/\/mc04.manuscriptcentral.com\/zoonoses\">https:\/\/mc04.manuscriptcentral.com\/zoonoses<\/a><\/p>\n<p>Please visit <a href=\"https:\/\/zoonoses-journal.org\/%20\">https:\/\/zoonoses-journal.org\/<\/a> to learn more about the journal.<\/p>\n<p><strong>Editorial Board:<\/strong> <a href=\"https:\/\/zoonoses-journal.org\/index.php\/editorial-board\/\">https:\/\/zoonoses-journal.org\/index.php\/editorial-board\/<\/a><\/p>\n<p><strong><em>Zoonoses<\/em><\/strong> is available on <a href=\"https:\/\/www.scienceopen.com\/search#collection\/839df240-327f-47dd-b636-9b728dff9700\">ScienceOpen<\/a> (<a href=\"https:\/\/www.scienceopen.com\/search#collection\/839df240-327f-47dd-b636-9b728dff9700\">https:\/\/www.scienceopen.com\/search#collection\/839df240-327f-47dd-b636-9b728dff9700<\/a>).<\/p>\n<p>Submissions may be made using <a href=\"https:\/\/mc04.manuscriptcentral.com\/zoonoses\">ScholarOne<\/a> (<a href=\"https:\/\/mc04.manuscriptcentral.com\/zoonoses\">https:\/\/mc04.manuscriptcentral.com\/zoonoses<\/a>).<\/p>\n<p>There are no author submission or article processing fees.<\/p>\n<p>Follow <strong><em>Zoonoses <\/em><\/strong>on Twitter <a href=\"https:\/\/twitter.com\/ZoonosesJ\">@ZoonosesJ<\/a>; <a href=\"https:\/\/www.facebook.com\/Zoonoses-Journal-100462755574114\">Facebook<\/a> (<a href=\"https:\/\/www.facebook.com\/Zoonoses-Journal-100462755574114\">https:\/\/www.facebook.com\/Zoonoses-Journal-100462755574114<\/a> ) and <a href=\"https:\/\/www.linkedin.com\/company\/zoonoses\/\">LinkedIn<\/a> (<a href=\"https:\/\/www.linkedin.com\/company\/zoonoses\/\">https:\/\/www.linkedin.com\/company\/zoonoses\/<\/a>)<strong>\u00a0<\/strong><\/p>\n<p><strong>eISSN <\/strong>2737-7474<\/p>\n<p><strong>ISSN<\/strong> 2737-7466<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Announcing a new article publication for Zoonoses journal. Bourbon virus (BRBV) was first isolated from a blood sample collected from a male patient living in Bourbon County, Kansas, during the spring of 2014. The patient later died because of complications associated with multiorgan failure. Several deaths due to BRBV infection have since been reported in [&hellip;]<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[138,135,137,136],"class_list":["post-690","post","type-post","status-publish","format-standard","hentry","category-news-and-events","tag-antiviral-agents","tag-bourbon-virus","tag-infection","tag-lone-star-tick"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Research Advances in Bourbon Virus, a Tick-borne Thogotovirus of the Orthomyxovirus Family - Zoonoses Journal<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/zoonoses-journal.org\/index.php\/2022\/06\/14\/research-advances-in-bourbon-virus-a-tick-borne-thogotovirus-of-the-orthomyxovirus-family\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research Advances in Bourbon Virus, a Tick-borne Thogotovirus of the Orthomyxovirus Family - Zoonoses Journal\" \/>\n<meta property=\"og:description\" content=\"Announcing a new article publication for Zoonoses journal. Bourbon virus (BRBV) was first isolated from a blood sample collected from a male patient living in Bourbon County, Kansas, during the spring of 2014. The patient later died because of complications associated with multiorgan failure. 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