{"id":601,"date":"2021-12-09T14:07:58","date_gmt":"2021-12-09T14:07:58","guid":{"rendered":"https:\/\/zoonoses-journal.org\/?p=601"},"modified":"2021-12-09T14:12:56","modified_gmt":"2021-12-09T14:12:56","slug":"zika-virus-overview-transmission-origin-pathogenesis-animal-model-and-diagnosis","status":"publish","type":"post","link":"https:\/\/zoonoses-journal.org\/index.php\/2021\/12\/09\/zika-virus-overview-transmission-origin-pathogenesis-animal-model-and-diagnosis\/","title":{"rendered":"Zika Virus Overview: Transmission, Origin, Pathogenesis, Animal Model and Diagnosis"},"content":{"rendered":"<p>Announcing a new article publication for<em> Zoonoses<\/em> journal. Dallas Vue and Qiyi Tang from Howard University College of Medicine, Washington, DC, USA review transmission, origin, pathogenesis, animal model and diagnosis of Zika Virus.<\/p>\n<p>Zika virus (ZIKV) was first discovered in 1947 in Uganda. ZIKV did not receive substantial attention until Brazil hosted the 2016 Summer Olympic Games, and ZIKV reached a global audience. ZIKV is a flavivirus transmitted chiefly through mosquito bites, sexual intercourse and, to a lesser extent, breastfeeding. The recent discovery of how ZIKV causes congenital neurodevelopmental defects, including microcephaly, has led to reevaluation of the importance of the interaction of ZIKV with centrosome organization, because centrosomes play an important role in cell division. When ZIKV disrupts centrosome organization and mitotic abnormalities, neural progenitor differentiation is altered, thereby resulting in cell cycle arrest, increased apoptosis and inhibition of neural progenitor cell differentiation; subsequently, abnormalities in neural cell development can result in microcephaly. To aid in the understanding of the importance of ZIKV infection, the authors of this article provide an overview of its history, transmission routes, pathogenesis, animal models and diagnosis.<strong>\u00a0<\/strong><\/p>\n<p><a href=\"https:\/\/doi.org\/10.15212\/ZOONOSES-2021-0017\">https:\/\/doi.org\/10.15212\/ZOONOSES-2021-0017<\/a><\/p>\n<p><strong>Article reference:<\/strong> Dallas Vue and Qiyi Tang. Zika Virus Overview: Transmission, Origin, Pathogenesis, Animal Model and Diagnosis.\u00a0<em>Zoonoses.\u00a0<\/em>Vol. 1(1). DOI: 10.15212\/ZOONOSES-2021-0017.<\/p>\n<p><strong>Keywords:<\/strong> Zika virus (ZIKV) centrosome, flavivirus, microcephaly<\/p>\n<p><em>Zoonoses<\/em> is fully open access journal for research scientists, physicians, veterinarians, and public health professionals working on diverse disciplinaries of zoonotic diseases.<\/p>\n<p><em>Zoonoses<\/em> is now open for submissions; articles can be submitted online at <a href=\"https:\/\/mc04.manuscriptcentral.com\/zoonoses\">https:\/\/mc04.manuscriptcentral.com\/zoonoses<\/a><\/p>\n<p>Please visit <a href=\"https:\/\/zoonoses-journal.org\/%20\">https:\/\/zoonoses-journal.org\/<\/a> to learn more about the journal.<\/p>\n<p><strong>Editorial Board:<\/strong> <a href=\"https:\/\/zoonoses-journal.org\/index.php\/editorial-board\/\">https:\/\/zoonoses-journal.org\/index.php\/editorial-board\/<\/a><\/p>\n<p><strong><em>Zoonoses<\/em><\/strong> is available on <a href=\"https:\/\/www.scienceopen.com\/search#collection\/839df240-327f-47dd-b636-9b728dff9700\">ScienceOpen<\/a> (<a href=\"https:\/\/www.scienceopen.com\/search#collection\/839df240-327f-47dd-b636-9b728dff9700\">https:\/\/www.scienceopen.com\/search#collection\/839df240-327f-47dd-b636-9b728dff9700<\/a>).<\/p>\n<p>Submissions may be made using <a href=\"https:\/\/mc04.manuscriptcentral.com\/zoonoses\">ScholarOne<\/a> (<a href=\"https:\/\/mc04.manuscriptcentral.com\/zoonoses\">https:\/\/mc04.manuscriptcentral.com\/zoonoses<\/a>).<\/p>\n<p>There are no author submission or article processing fees.<\/p>\n<p>Follow <strong><em>Zoonoses <\/em><\/strong>on Twitter <a href=\"https:\/\/twitter.com\/ZoonosesJ\">@ZoonosesJ<\/a>; <a href=\"https:\/\/www.facebook.com\/Zoonoses-Journal-100462755574114\">Facebook<\/a> (<a href=\"https:\/\/www.facebook.com\/Zoonoses-Journal-100462755574114\">https:\/\/www.facebook.com\/Zoonoses-Journal-100462755574114<\/a> ) and <a href=\"https:\/\/www.linkedin.com\/company\/zoonoses\/\">LinkedIn<\/a> (<a href=\"https:\/\/www.linkedin.com\/company\/zoonoses\/\">https:\/\/www.linkedin.com\/company\/zoonoses\/<\/a>)<\/p>\n<p><strong>eISSN <\/strong>2737-7474<\/p>\n<p><strong>ISSN<\/strong> 2737-7466<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Announcing a new article publication for Zoonoses journal. Dallas Vue and Qiyi Tang from Howard University College of Medicine, Washington, DC, USA review transmission, origin, pathogenesis, animal model and diagnosis of Zika Virus. Zika virus (ZIKV) was first discovered in 1947 in Uganda. ZIKV did not receive substantial attention until Brazil hosted the 2016 Summer [&hellip;]<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[81,82,80],"class_list":["post-601","post","type-post","status-publish","format-standard","hentry","category-news-and-events","tag-flavivirus","tag-microcephaly","tag-zika-virus-zikv-centrosome"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Zika Virus Overview: Transmission, Origin, Pathogenesis, Animal Model and Diagnosis - Zoonoses Journal<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/zoonoses-journal.org\/index.php\/2021\/12\/09\/zika-virus-overview-transmission-origin-pathogenesis-animal-model-and-diagnosis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Zika Virus Overview: Transmission, Origin, Pathogenesis, Animal Model and Diagnosis - Zoonoses Journal\" \/>\n<meta property=\"og:description\" content=\"Announcing a new article publication for Zoonoses journal. Dallas Vue and Qiyi Tang from Howard University College of Medicine, Washington, DC, USA review transmission, origin, pathogenesis, animal model and diagnosis of Zika Virus. Zika virus (ZIKV) was first discovered in 1947 in Uganda. 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