{"id":1725,"date":"2025-05-06T13:06:44","date_gmt":"2025-05-06T13:06:44","guid":{"rendered":"https:\/\/zoonoses-journal.org\/?p=1725"},"modified":"2026-07-13T09:06:56","modified_gmt":"2026-07-13T09:06:56","slug":"sftsv-vaccine-strategies-glycoproteins-np-immunogenicity","status":"publish","type":"post","link":"https:\/\/zoonoses-journal.org\/index.php\/2025\/05\/06\/sftsv-vaccine-strategies-glycoproteins-np-immunogenicity\/","title":{"rendered":"Current Advances in Vaccine Development for Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV)"},"content":{"rendered":"<p><img decoding=\"async\" class=\"alignright size-thumbnail wp-image-1726\" src=\"https:\/\/zoonoses-journal.org\/wp-content\/uploads\/2025\/05\/zoonoses20250005_fig1-150x150.jpg\" alt=\"\" width=\"150\" height=\"150\" srcset=\"https:\/\/zoonoses-journal.org\/wp-content\/uploads\/2025\/05\/zoonoses20250005_fig1-150x150.jpg 150w, https:\/\/zoonoses-journal.org\/wp-content\/uploads\/2025\/05\/zoonoses20250005_fig1-300x300.jpg 300w, https:\/\/zoonoses-journal.org\/wp-content\/uploads\/2025\/05\/zoonoses20250005_fig1-1020x1024.jpg 1020w, https:\/\/zoonoses-journal.org\/wp-content\/uploads\/2025\/05\/zoonoses20250005_fig1-768x771.jpg 768w, https:\/\/zoonoses-journal.org\/wp-content\/uploads\/2025\/05\/zoonoses20250005_fig1-1320x1325.jpg 1320w, https:\/\/zoonoses-journal.org\/wp-content\/uploads\/2025\/05\/zoonoses20250005_fig1.jpg 1417w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/>Announcing a new article publication for <em>Zoonoses<\/em> journal. Severe fever with thrombocytopenia syndrome (SFTS), caused by the tick-borne severe fever with thrombocytopenia syndrome virus (SFTSV), is a disease that is endemic to East Asia and has mortality rates reaching 30%. Despite its substantial public health impact, no vaccines or antiviral treatments are currently available. The SFTSV genome encodes key structural proteins, including glycoproteins (Gn and Gc) and nucleocapsid protein (NP), which serve as critical vaccine targets. <!--more--><\/p>\n<p>Read more: <a href=\"https:\/\/www.scienceopen.com\/hosted-document?doi=10.15212\/ZOONOSES-2025-0005\">https:\/\/www.scienceopen.com\/hosted-document?doi=10.15212\/ZOONOSES-2025-0005<\/a><\/p>\n<p>This article reviews the current status of SFTSV-related vaccine platforms\u2014such as viral vectors, inactivated viruses, DNA, mRNA, and protein-based approaches\u2014and highlights the immune responses elicited by these platforms against key antigens, particularly glycoproteins and NP. Future research directions are additionally proposed to accelerate the development of effective SFTSV vaccines by leveraging insights from existing studies.<\/p>\n<p><em>Zoonoses<\/em> is fully open access journal for research scientists, physicians, veterinarians, and public health professionals working on diverse disciplinaries of zoonotic diseases. Please visit <a href=\"https:\/\/zoonoses-journal.org\/%20\">https:\/\/zoonoses-journal.org\/<\/a> to learn more about the journal.<\/p>\n<p><em>Zoonoses<\/em> is now open for submissions; articles can be submitted online at <a href=\"https:\/\/mc04.manuscriptcentral.com\/zoonoses\">https:\/\/mc04.manuscriptcentral.com\/zoonoses<\/a><\/p>\n<p>There are no author submission or article processing fees.<\/p>\n<p><strong>Editorial Board:<\/strong> <a href=\"https:\/\/zoonoses-journal.org\/index.php\/editorial-board\/\">https:\/\/zoonoses-journal.org\/index.php\/editorial-board\/<\/a><\/p>\n<p><strong><em>Zoonoses<\/em><\/strong> is available on <a href=\"https:\/\/www.scienceopen.com\/search#collection\/839df240-327f-47dd-b636-9b728dff9700\">ScienceOpen<\/a> (<a href=\"https:\/\/www.scienceopen.com\/search#collection\/839df240-327f-47dd-b636-9b728dff9700\">https:\/\/www.scienceopen.com\/search#collection\/839df240-327f-47dd-b636-9b728dff9700<\/a>).<\/p>\n<p>Follow <strong><em>Zoonoses <\/em><\/strong>on Twitter <a href=\"https:\/\/twitter.com\/ZoonosesJ\">@ZoonosesJ<\/a>; <a href=\"https:\/\/www.facebook.com\/Zoonoses-Journal-100462755574114\">Facebook<\/a> (<a href=\"https:\/\/www.facebook.com\/Zoonoses-Journal-100462755574114\">https:\/\/www.facebook.com\/Zoonoses-Journal-100462755574114<\/a> ) and <a href=\"https:\/\/www.linkedin.com\/company\/zoonoses\/\">LinkedIn<\/a> (<a href=\"https:\/\/www.linkedin.com\/company\/zoonoses\/\">https:\/\/www.linkedin.com\/company\/zoonoses\/<\/a>)<strong>\u00a0<\/strong><\/p>\n<p><strong>eISSN <\/strong>2737-7474<\/p>\n<p><strong>ISSN<\/strong> 2737-7466<\/p>\n<p>Hyo-Jin Ro and Nam-Hyuk Cho. Current Advances in Vaccine Development for Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV).\u00a0<em>Zoonoses.\u00a0<\/em>2025. Vol. 5(1). DOI: 10.15212\/ZOONOSES-2025-0005<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Announcing a new article publication for Zoonoses journal. Severe fever with thrombocytopenia syndrome (SFTS), caused by the tick-borne severe fever with thrombocytopenia syndrome virus (SFTSV), is a disease that is endemic to East Asia and has mortality rates reaching 30%. Despite its substantial public health impact, no vaccines or antiviral treatments are currently available. The [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":1726,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[438,305,618,617,436,346,307],"class_list":["post-1725","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-and-events","tag-arbovirus","tag-pathogen","tag-sftsv","tag-tick","tag-vector","tag-viral-diseases","tag-zoonoses"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Current Advances in Vaccine Development for Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV)<\/title>\n<meta name=\"description\" content=\"Severe Fever with Thrombocytopenia Syndrome Virus vaccines target glycoproteins and NP; review highlights platforms and immune responses.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/zoonoses-journal.org\/index.php\/2025\/05\/06\/sftsv-vaccine-strategies-glycoproteins-np-immunogenicity\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Current Advances in Vaccine Development for Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV)\" \/>\n<meta property=\"og:description\" content=\"Severe Fever with Thrombocytopenia Syndrome Virus vaccines target glycoproteins and NP; review highlights platforms and immune responses.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/zoonoses-journal.org\/index.php\/2025\/05\/06\/sftsv-vaccine-strategies-glycoproteins-np-immunogenicity\/\" \/>\n<meta property=\"og:site_name\" content=\"Zoonoses Journal\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/Zoonoses-Journal-100462755574114\" \/>\n<meta property=\"article:published_time\" content=\"2025-05-06T13:06:44+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-07-13T09:06:56+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/zoonoses-journal.org\/wp-content\/uploads\/2025\/05\/zoonoses20250005_fig1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1417\" \/>\n\t<meta property=\"og:image:height\" content=\"1422\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Nam-Hyuk Cho\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@ZoonosesJ\" \/>\n<meta name=\"twitter:site\" content=\"@ZoonosesJ\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Nam-Hyuk Cho\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/zoonoses-journal.org\\\/index.php\\\/2025\\\/05\\\/06\\\/sftsv-vaccine-strategies-glycoproteins-np-immunogenicity\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/zoonoses-journal.org\\\/index.php\\\/2025\\\/05\\\/06\\\/sftsv-vaccine-strategies-glycoproteins-np-immunogenicity\\\/\"},\"author\":{\"name\":\"Nam-Hyuk Cho\",\"@id\":\"https:\\\/\\\/zoonoses-journal.org\\\/#\\\/schema\\\/person\\\/32d651c0e99a7cc4ab2c74712d3b1d03\"},\"headline\":\"Current Advances in Vaccine Development for Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV)\",\"datePublished\":\"2025-05-06T13:06:44+00:00\",\"dateModified\":\"2026-07-13T09:06:56+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/zoonoses-journal.org\\\/index.php\\\/2025\\\/05\\\/06\\\/sftsv-vaccine-strategies-glycoproteins-np-immunogenicity\\\/\"},\"wordCount\":286,\"publisher\":{\"@id\":\"https:\\\/\\\/zoonoses-journal.org\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/zoonoses-journal.org\\\/index.php\\\/2025\\\/05\\\/06\\\/sftsv-vaccine-strategies-glycoproteins-np-immunogenicity\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/zoonoses-journal.org\\\/wp-content\\\/uploads\\\/2025\\\/05\\\/zoonoses20250005_fig1.jpg\",\"keywords\":[\"arbovirus\",\"pathogen\",\"SFTSV\",\"Tick\",\"Vector\",\"Viral diseases\",\"zoonoses\"],\"articleSection\":[\"News and Events\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/zoonoses-journal.org\\\/index.php\\\/2025\\\/05\\\/06\\\/sftsv-vaccine-strategies-glycoproteins-np-immunogenicity\\\/\",\"url\":\"https:\\\/\\\/zoonoses-journal.org\\\/index.php\\\/2025\\\/05\\\/06\\\/sftsv-vaccine-strategies-glycoproteins-np-immunogenicity\\\/\",\"name\":\"Current Advances in Vaccine Development for Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV)\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/zoonoses-journal.org\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/zoonoses-journal.org\\\/index.php\\\/2025\\\/05\\\/06\\\/sftsv-vaccine-strategies-glycoproteins-np-immunogenicity\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/zoonoses-journal.org\\\/index.php\\\/2025\\\/05\\\/06\\\/sftsv-vaccine-strategies-glycoproteins-np-immunogenicity\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/zoonoses-journal.org\\\/wp-content\\\/uploads\\\/2025\\\/05\\\/zoonoses20250005_fig1.jpg\",\"datePublished\":\"2025-05-06T13:06:44+00:00\",\"dateModified\":\"2026-07-13T09:06:56+00:00\",\"description\":\"Severe Fever with Thrombocytopenia Syndrome Virus vaccines target glycoproteins and NP; 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